Unit title & code :- BHS021-2
Assignment number and title :- Referral Assignment
Assignment type :- PCCAL simulation data analysis
Weighting of assignment :- 40%
Size or length of assessment :- 1500 words
BHS021-2 Pharmacology Assignment – UK
Unit learning outcomes 1.
1.Demonstrate understanding of the molecular cellular and physiological basis of drug action and apply the knowledge to the clinical treatment of human diseases.
2.Correlation of different types of drugs with the types of conditions that they are used to treat.
What am I required to do in this assignment?
The experiment was performed to measure the effect of different doses of cyclopentolate as an antagonist of muscurinic acid receptor on mouse ileum. Analyze the available data shown in the table 1 and answer the questions associated with it. (100%).
1) Using Microsoft Excel, plot dose response curves for muscurinic acid-induced contractions of mouse ileum in the presence and absence of the three concentrations of cyclopentolate.
2) From the dose response curves, determine the ED50 values for muscurinic acid. Is the maximum response produced by muscurinic acid depressed in the presence of cyclopentolate?
3) You will need to search the scientific literature in order to discuss an agonist and antagonist drug interaction that have been used in this experiment.
4) You are expected to prepare a report containing a brief introduction, dose-responses curves, the ED50 values calculations a brief discussion related to your results and References. For further detail for each section, see outline of report structure as shown below.
5) The report should be no more than 1500 words (excluding references). The report should be structured like a research article in a scientific journal (see details below) and should be submitted via BREO only.
BHS021-2 Pharmacology Assignment – UK
Outline Of Report Structure :-
Your report should contain four sections: Introduction, Results, Discussion and References. Each section should be clearly labelled. Clarity of English language and presentation is essential throughout.
Introduction :
This section should represent 30% of your report. Describe the pharmacology of receptor agonists and different types of receptor antagonists by using relevant literature.
Results:
This section should represent 25% of your report. Data should be presented in tables. A graph should be provided to show the dose-response curves with ED50. You will draw 4 dose-response curves in the same graph (one for the agonist only, and the other three curves for the agonist + different concentrations of antagonist). The graph should be prepared using Excel. The figure and table should be separately numbered and clearly labelled. You should add figure legend to the figure. The Results should describe your findings/observations, but not interpret their meaning.
Results:
This section should represent 25% of your report. Data should be presented in tables. A graph should be provided to show the dose- response curves with ED50. You will draw 4 dose-response curves in the same graph (one for the agonist only, and the other three curves for the agonist + different concentrations of antagonist). The graph should be prepared using Excel. The figure and table should be separately numbered and clearly labelled. You should add figure legend to the figure. The Results should describe your findings/observations, but not interpret their meaning.
BHS021-2 Pharmacology Assignment – UK
What do I need to do to pass? (Threshold Expectations from UIF)
i. Demonstrate appropriate analysis of given data
ii. Produce a scientific report according to expectations described in the assignment brief.
How do I produce high quality work that merits a good grade?
A high quality report should
• be created electronically using Microsoft word and contain graph created electronically using Excel
• contain a title page giving the assessment title, unit code, assessment number, your student number and your final word count (excluding references)
• contain appropriately labelled table and figure referred to in the main text
• contain appropriate examples of how calculations were performed
• Follow the word-limit requirement (1500 max excluding references)
How does this assignment relate to what we are doing in scheduled sessions?
This report is directly related to the taught element delivered during lectures. More specifically lectures related to drug delivery drug-receptor activation pharma cokinetics and pharmacodynamics.
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